Jurnal Jamu Indonesia

Identification of Java Tea Adulteration by Babadotan and Tekelan using Machine Learning

Ary Prabowo, Wisnu Ananta Kusuma, Annisa, Mohamad Rafi — Fri, 30 Dec 2022 00:00:00 +0700

Java Tea (Orthosiphon aristatus) is a common herbal medicinal plant that functions as a health treatment and treats various diseases. The high demand for Java Tea causes high prices and a decrease in the amount of medicinal plant raw materials, causing various quality control problems such as the content of various bioactive components and adulteration from babadotan and tekelan. So far, the detection of adulteration has been carried out by various analyzes, including chemical analysis and statistical methods to process data. The data used is of high dimension with a very high-density level, thus causing difficulties in classification. The mixed data of Orthosiphon aristatus consists of 1201 features with a total sample of 216. This study uses a Random Forest (RF) method with a total of 100 trees, and the RF method is combined with the Recursive Feature Elimination (RFE) method. In the RF and RFE that can be produced, the optimum value for the number of features is 244. The experimental evaluation results revealed that the proposed method could achieve a high accuracy of 81.82% in identifying Orthosiphon aristatus.

Antioxidant Capacity, Total Phenolic, and Flavonoid Content from Java Tea (Orthosiphon aristatus) Extracts

Zulhan Arif, Aurentinus Zalukhu, Alfi Hudatul Karomah, Mohamad Rafi — Fri, 30 Dec 2022 00:00:00 +0700

Orthosiphon aristatus, known as kumis kucing in Indonesia, has some biological activity, i.e., as an anti-inflammatory, fever, rheumatism, diabetes, and kidney stone. This plant is also known for being rich in phenolic compounds such as flavonoids. In this study, we would like to compare the antioxidant activity, total phenolics, and flavonoid content from the stems and leaves of Orthosiphon aristatus extracted with water and ethanol by maceration. The yield stem and leaves of the water extract are 12.98-31.28%, and ethanol extract 3.58 - 9.82% (dry basis). The stem and leaves water extract contains a phenolic of 7.82-26.43 (mg GAE/g) and ethanol extract of 2.27-7.84 (mg GAE/g). Water extract Orthosiphon aristatus flavonoid content is 1.23-2.86 (mg EK/g), and ethanol extract is 1.09-3.95 (mg EK/g). The antioxidant activity of ethanol (IC₅₀), extract from leaves was 123.91 (µg/mL) and from stems was 125.50 (µg/mL), while IC₅₀of water extract from leaves was 114.70 (µg/mL) and from stems was 125.03 (µg/mL). The correlation test result of active compounds using linear regression is phenolic compounds with antioxidants stronger than flavonoids. The qualitative thin-layer chromatography fingerprint analysis showed that ethanol and water extract contained natural sinensetin compounds.

Antidiabetic Activity of Manonjaya Snakefruit Skin Extract with Zebra Fish (Danio rerio) as Animal Model

Eti Rohaeti, Dea Nurafifah, Irmanida Batubara — Fri, 30 Dec 2022 00:00:00 +0700

This research aimed to determine the active fraction and profile of active compounds in Manonjaya sSnakefruit skin extract that can be used as antidiabetic and the antidiabetic activity using zebra fish. Manonjaya sSnakefruit skin was extracted by maceration using 70% ethanol and then fractionated using n-hexane, ethyl acetate and methanol. The ethyl acetate fraction showed the highest yield and total phenolic content as well as the strongest α-glucosidase inhibition with an inhibition percentage of 64.43%. The ethyl acetate fraction provided the most active spot as an α-glucosidase inhibitor. The profile of active compounds that act as antidiabetic compound is flavonoid from glycosylflavone and flavone groups. Antidiabetic activity using zebra fish was indicates that Manonjaya Snakefruit skin extract from ethanol extract and ethyl acetate fraction can decrease blood sugar level of zebra fish after induced with alloxan. The crude extract group had 54.51% lower sugar content than the induction group and 41.70% lower than the negative control. Meanwhile, the ethyl acetate fraction group had 65.10% lower sugar content than the induction group and 55.27% lower than the negative control.

Utilizing Program of Vacant Land on Public Facilities for Diabetes Mellitus Self-Medication Parks in Benteng Village, Bogor Regency

Ninuk Purnaningsih Purnaningsih, Siti Sa’diah, Qodarian Pramukanto — Fri, 30 Dec 2022 00:00:00 +0700

The prevalence of diabetes in Indonesia has increased substantially in the last 30 years, where individual chances of developing diabetes are higher for women than for men; and level of education is negatively related to diabetes mellitus. Independent therapy garden, is one of the functions of public park which is designed thematically for therapy (medication).The objectives of Program are: (1) Development of a participatory Diabetes Mellitus Self-therapy Garden at partner locations; (2) Cultivation training and education in using/processing of medicinal plants for self-therapy for Diabetes. Program partners are the Kecapi Posyandu RW 6 Benteng Village Bogor Regency, West Java Province. Partner problems are: (1) There are a large number of elderly people who have the potential to suffer from Type 2 Diabetes; (2) Lack of knowledge of partners and residents around partner locations about Diabetes: its characteristics, treatment and prevention; (3) Lack of skills in cultivating and processing of medicinal plants to maintain health, especially diabetes. The participatory approach was carried out by involving partners from the beginning of the program, started from discussing the activity plan, determining the location of the public facility land to be built into a therapy park, and determining program participants. The determination of the location of the park was chosen based on area that was easily visited by residents, so that they can interact with fellow residents in the park. Education about diabetes therapy was carried out by conveying information about diabetes mellitus and how to handle it. Education on the use of medicinal plants, processing them, concocting them, was carried out in practice. There has been an increase in knowledge, skills, and positive attitudes in the prevention and treatment of diabetes independently by partners. The sustainability of the program is carried out by providing diabetes self-therapy manuals, and mentoring through groups through periodic discussions.

Phytochemical, Antioxidant and Antibacterial Screening of Orthosiphon stamineus Leaf Extract Two Phenotypes

Fri, 30 Dec 2022 00:00:00 +0700

Kumis kucing (Orthosiphon stamineus) is a medicinal plant that can treat various diseases. Kumis kucing has been known to contain bioactive compounds, namely polyphenol, alkaloid, and terpenoid which have antioxidant, antibacterial, antiviral, anti-inflammatory, anti-allergic and anti-cancer activities. This study aims to determine the phytochemical content, antioxidant activity, and antibacterial activity of the cat's whiskers leaf extract. Kumis Kucing leaf extract was obtained by sonication-maceration method. Antioxidant activity test of cat's kumis leaf extract was tested using the CUPRAC and ABTS methods. The results showed that the kumis kucing’s leaf extract contains bioactive compounds of polyphenol, alkaloid, and terpenoid. The highest average antioxidant activity was produced by the purple phenotype cat whiskers leaf extract using the ABTS method, which was 168.68 µg TE/g dry weight. The highest average antibacterial activity in Escherichia coli strain was obtained from leaf extract of purple phenotype cat whiskers (U2) with an inhibition zone diameter of 3.2 mm.

Editorial

Waras Nurcholis — Thu, 12 Jan 2023 00:00:00 +0700

Puji dan syukur kami panjatkan kepada Tuhan Yang Maha Esa atas rahmat dan hidayahNya, Jurnal Jamu Indonesia Volume 7 No 3 tahun 2022 dapat diterbitkan. Jurnal Jamu Indonesia merupakan media untuk diseminasi hasil penelitian yang berkaitan dengan jamu di Indonesia. Jamu telah dikenal lama penduduk Indonesia sebagai salah satu pengobatan. Berbagai tanaman di Indonesia sangat berpotensi sebagai jamu. Penelitian tanaman obat dari bagian daun, batang, dan rimpang tanaman telah banyak dilakukan dan terus berkembang.

Jurnal Jamu Indonesia pada Volume 7 No 3 Tahun 2022 terdiri atas 5 naskah. Naskah diterbitkan memiliki tema beragam, meliputi: Identifikasi Pemalsuan Kumis Kucing Dari Babadotan Dan Tekelan Menggunakan Machine Learning; Kapasitas Antioksidan, Kadar Fenolik, dan Flavonoid Total Ekstrak Air dan Etanol Kumis Kucing (Orthosiphon aristatus); Program Pemanfaatan Lahan Kosong Fasilitas Umum untuk Taman Terapi Mandiri Diabetes Mellitus di Desa Benteng Kabupaten Bogor; Skrining Fitokimia, Antioksidan, dan Antibakteri Ekstrak Daun Orthosiphon stamineus Dua Fenotipe dan Aktivitas Antidiabetes Ekstrak Kulit Buah Salak Manonjaya dengan Ikan Zebra (Danio rerio) Sebagai Hewan Model.

Redaksi mengucapkan terima kasih kepada seluruh penulis atas partisipasinya dalam berbagi hasil penelitiannya melalui publikasi di Jurnal Jamu Indonesia. Redaksi juga mengucapkan terima kasih kepada seluruh reviewer atas partisipasinya dalam meningkatkan kualitas tulisan naskah jurnal di edisi ini. Semua hasil karya tersebut akan diarsipkan sebagai dokumentasi berharga demi terjaganya informasi yang dapat menjadi sumber pengembangan ilmu pengetahuan di masa depan. Kontribusi publikasi peneliti-peneliti dan pejuang Jamu Indonesia terus kami harapkan untuk dapat disampaikan di dalam Jurnal Jamu Indonesia ini. Peningkatan kontribusi jumlah dan kualitas tulisan yang telah dan akan dimasukkan akan dapat membantu pengembangan jurnal ini, dan pada saatnya diharapkan juga dapat menjadikan Jurnal Jamu Indonesia menjadi referensi baik secara nasional, maupun internasional.

Desember 2022
Waras Nurcholis
Wakil Ketua Dewan Redaksi

Indeks

Titis Arifiana — Thu, 12 Jan 2023 00:00:00 +0700

Seluruh penulis yang artikel ilmiahnya diterbitkan di Jurnal Jamu Indonesia Volume 7 Tahun 2022 dituliskan pada daftar berikut yang diurut secara abjad dilengkapi dengan nomor dan halaman.