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Submitted
November 25, 2021
Accepted
August 3, 2022
Published
August 30, 2022
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Abstract
The flavonoid compound in Noni leaves (Morinda citrifolia) are efficacious as free radical scavengers. This research aimed to know the influence of the ratio of materials and a solvent (M:S=1:10; M:S=1:15; M:S=1:20) on the flavonoid content and free radical scavenging activity of extract of noni leaves. Extraction was carried out using the Microwave Assisted Extraction method and the free radical scavenging activity were determined by 1,1-diphenyl-2-picrylhydrazyl (DPPH). The results showed that the material-solvent ratio had a significant effect on the yield, total flavonoid content, and free radical scavenging activity. The material to solvent ratio 1: 20 resulted in the highest yield, total flavonoid content, and free radical scavenging activity compared to other solvent-solvent ratios.
Keywords
Morinda citrifolia
Leaves
total flavonoid content
free radical scavenging activity
Article Details
How to Cite
Ramayani, S. L., Fitria Rohmawati, & Yasmine Savira Rahmadani. (2022). The effect of Material to Solvent Ratio to The Flavonoid Content and Free Radical Scavenging Activity of Extract of Morinda Citrifolia L Leaves. Jurnal Jamu Indonesia, 7(2), 56–61. https://doi.org/10.29244/jji.v7i2.245
References
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Ahmad, A.L., C.Y. Chan, S.R.A. Shukor and M.D. Mashitah. 2008. Recovery of oil and carotenes from palm oil Mill. effluent. Chemical Engineering Journal 141: 383-386.
Arnanda, P., Q., Nuwarda, R., F., 2019, Review Article : Penggunaan Radiofarmaka Teknesium-99M dari Senyawa Glutation dan Senyawa Flavonoid Sebagai Deteksi Dini Radikal Bebas Pemicu Kanker, Farmaka, Volume 17 Nomor 2 (236-243).
Chang, C. C., Yang, M.H., Chern, J.C. 2002. Estimation of Total Flavonoid
Content in Propolis by Two Complementary Colorimetric Methods.
Journal of Food and Drug Analysis 10: 178-182
Dewi, Shinta R., Ulya, Naily., dan Argo, Bambang D. 2018. Kandungan Flavonoid dan Aktivitas Antioksidan Ekstrak Pleurotus ostreatus. Jurnal Rona Teknik Pertanian.
Halliwell, B dan Gutteridge, J.M.C. 2000. Free Radical in Biology and Medicine. Oxford University Press. New York.
Hanani, E. 2015. Analisis Fitokimia. Buku Kedokteran EGC. Jakarta.
Hardiningtyas, S., D., Purwaningsih, S., Handharyani, E., 2014, Aktivitas Antioksidan dan Efek Hepatoprotektif Daun Bakau Api-api Putih, JPHPI, Volume 17 Nomor 1 (80-91)
Inggrid, H.M., dan Santoso, H., 2014, Ekstraksi Antioksidan dan Senyawa Aktif Dari Buah Kiwi (Actinidia deliciosa), Lembaga Penelitian dan Pengabdian Masyarakat. Universitas Katolik Parahyangan
Jain, T., A. Vyas, V. Jain, R. Pandey, & S. S. Shukla. 2009.Microwave-Assisted Extraction for Phytoconstituens An Overview.Asian Journal Research Chemistry, 1(2), 19-25.
Rohman, A., Riyanto, S., Hidayati, N.,K., 2007, Aktivitas Antioksidan, Kandungan Fenolik Total dan Flavonoid Total Daun Mengkudu, Agritech, Volume 27 Nomor 4 (147-151)
Thangraj, P. 2016. Pharmacologycal Assay of Plant-Based Natural Products. Springer International Publisher. Switzerland.
References
Afandi, Mochammad. 2013. Aplikasi Pakan Komersil Yang Disubstitusikan Tepung Silase Daun Mengkudu Dengan Inokulan Khamir Laut Sebagai Pakan Ikan Sidat (Anguilla bicolor). Skripsi. Universitas Hang Tuah: Surabaya.
Ahmad, A.L., C.Y. Chan, S.R.A. Shukor and M.D. Mashitah. 2008. Recovery of oil and carotenes from palm oil Mill. effluent. Chemical Engineering Journal 141: 383-386.
Arnanda, P., Q., Nuwarda, R., F., 2019, Review Article : Penggunaan Radiofarmaka Teknesium-99M dari Senyawa Glutation dan Senyawa Flavonoid Sebagai Deteksi Dini Radikal Bebas Pemicu Kanker, Farmaka, Volume 17 Nomor 2 (236-243).
Chang, C. C., Yang, M.H., Chern, J.C. 2002. Estimation of Total Flavonoid
Content in Propolis by Two Complementary Colorimetric Methods.
Journal of Food and Drug Analysis 10: 178-182
Dewi, Shinta R., Ulya, Naily., dan Argo, Bambang D. 2018. Kandungan Flavonoid dan Aktivitas Antioksidan Ekstrak Pleurotus ostreatus. Jurnal Rona Teknik Pertanian.
Halliwell, B dan Gutteridge, J.M.C. 2000. Free Radical in Biology and Medicine. Oxford University Press. New York.
Hanani, E. 2015. Analisis Fitokimia. Buku Kedokteran EGC. Jakarta.
Hardiningtyas, S., D., Purwaningsih, S., Handharyani, E., 2014, Aktivitas Antioksidan dan Efek Hepatoprotektif Daun Bakau Api-api Putih, JPHPI, Volume 17 Nomor 1 (80-91)
Inggrid, H.M., dan Santoso, H., 2014, Ekstraksi Antioksidan dan Senyawa Aktif Dari Buah Kiwi (Actinidia deliciosa), Lembaga Penelitian dan Pengabdian Masyarakat. Universitas Katolik Parahyangan
Jain, T., A. Vyas, V. Jain, R. Pandey, & S. S. Shukla. 2009.Microwave-Assisted Extraction for Phytoconstituens An Overview.Asian Journal Research Chemistry, 1(2), 19-25.
Rohman, A., Riyanto, S., Hidayati, N.,K., 2007, Aktivitas Antioksidan, Kandungan Fenolik Total dan Flavonoid Total Daun Mengkudu, Agritech, Volume 27 Nomor 4 (147-151)
Thangraj, P. 2016. Pharmacologycal Assay of Plant-Based Natural Products. Springer International Publisher. Switzerland.
Ahmad, A.L., C.Y. Chan, S.R.A. Shukor and M.D. Mashitah. 2008. Recovery of oil and carotenes from palm oil Mill. effluent. Chemical Engineering Journal 141: 383-386.
Arnanda, P., Q., Nuwarda, R., F., 2019, Review Article : Penggunaan Radiofarmaka Teknesium-99M dari Senyawa Glutation dan Senyawa Flavonoid Sebagai Deteksi Dini Radikal Bebas Pemicu Kanker, Farmaka, Volume 17 Nomor 2 (236-243).
Chang, C. C., Yang, M.H., Chern, J.C. 2002. Estimation of Total Flavonoid
Content in Propolis by Two Complementary Colorimetric Methods.
Journal of Food and Drug Analysis 10: 178-182
Dewi, Shinta R., Ulya, Naily., dan Argo, Bambang D. 2018. Kandungan Flavonoid dan Aktivitas Antioksidan Ekstrak Pleurotus ostreatus. Jurnal Rona Teknik Pertanian.
Halliwell, B dan Gutteridge, J.M.C. 2000. Free Radical in Biology and Medicine. Oxford University Press. New York.
Hanani, E. 2015. Analisis Fitokimia. Buku Kedokteran EGC. Jakarta.
Hardiningtyas, S., D., Purwaningsih, S., Handharyani, E., 2014, Aktivitas Antioksidan dan Efek Hepatoprotektif Daun Bakau Api-api Putih, JPHPI, Volume 17 Nomor 1 (80-91)
Inggrid, H.M., dan Santoso, H., 2014, Ekstraksi Antioksidan dan Senyawa Aktif Dari Buah Kiwi (Actinidia deliciosa), Lembaga Penelitian dan Pengabdian Masyarakat. Universitas Katolik Parahyangan
Jain, T., A. Vyas, V. Jain, R. Pandey, & S. S. Shukla. 2009.Microwave-Assisted Extraction for Phytoconstituens An Overview.Asian Journal Research Chemistry, 1(2), 19-25.
Rohman, A., Riyanto, S., Hidayati, N.,K., 2007, Aktivitas Antioksidan, Kandungan Fenolik Total dan Flavonoid Total Daun Mengkudu, Agritech, Volume 27 Nomor 4 (147-151)
Thangraj, P. 2016. Pharmacologycal Assay of Plant-Based Natural Products. Springer International Publisher. Switzerland.